COURSE NUMBER: BIO 446
CREDIT HOURS: 4.0
INSTRUCTOR: DR. SAMIR S. RAYCHOUDHURY
OFFICE LOCATION: ALU 206
E MAIL: sraychoudhury@crle.com
Phone: 255-1781
CLASS SCHEDULE: LECTURE MWF 1-1:50 PM ALU 302
LAB W 3-5 PM ALU 216
REQUIRED TEXTBOOK:
Human Physiology, 7th Edition, by Stuart Ira Fox, WCB McGraw-Hill Publishers, Dubuque, IA, USA.
LABORATORY MANUAL:
Students are required to perform selected laboratory experimental exercises as prepared by the instructor. Students will be asked to make their own laboratory reports. No formal laboratory manual is required. However, the following laboratory guide will be consulted for studying laboratory of the Vertebrate Physiology course:
1. A Laboratory Textbook of Anatomy and Physiology by Donnersberger, Lesak and Timmons, D.C. Heath and Co., Lexington, USA.
COURSE DESCRIPTION:
Basic functions of the vertebrate body are studied in terms of physical and chemical principles. The important functions of the circulatory, digestive, respiratory, glandular, muscular, nervous and reproductive systems are discussed. Three 1-hour lecture periods and one 3-hour laboratory period. Prerequisite: Bio 242, Chem 242, and Phys 241.
INTRODUCTION:
The course is offered as an individualized instruction course within the framework of the conventional semester system. Some course activities are designed for the students to complete at one's own space and others are planned to complete during the scheduled lecture and laboratory periods. Individualized instruction puts maximum responsibility upon the student to complete all given assignments on time. The role of the instructor is to create a situation conductive to individual learning by providing directions, facility and motivation. The instructor will use multimedia including computer technology to teach the course. The teaching method will involve the following:
a. Reading and textbook assignments.
b. Laboratory experiments and reports.
c. Current professional articles review from 1998-2003 scientific journals.
d. Expert visit in the related field of physiology.
e. Films and videotape presentations and reports.
f. Tutoring by interactive Physiology CD.
g. Information dissemination from World Wide Webs.
Students are expected to attend classes regularly and should read the assigned chapters from the textbook for each unit before and after the classroom lecture period. The students will be asked to write reports on selected topics related to the course. All assignments are due on time as determined by the instructor.
Students are required to keep and maintain a laboratory data notebook. They will be asked to work in assigned groups. Each group will be responsible for its own lab preparations, set-ups and experiments.
GENERAL OBJECTIVES:
The students should achieve the following objectives:
1. Describe the hierarchical organization of the various parts of complex living organisms.
2. Identify the components of a cell. State the unique properties of water that are of biological significance and specify the major classes of organic components found in cell.
3. List eight physiological properties of protoplasm and explain the importance of each in the functioning of living organisms.
4. Understand the concepts of structure-function relationships in a manner that will allow the students to visualize the eleven organ systems and their role in homeostasis.
5. Describe the structure and functions of cell membrane and cytoplasmic organelles.
6. Analyze the role of solutions, colloidal systems, suspensions, emulsion, surface tension, absorption, Brownian movement, electrical properties and other properties of gels in living organisms.
7. Explain the physiology of nervous system, muscular system, sense organs and reproductive system.
8. Discuss the significance of blood circulation and other tissue fluids.
9. Evaluate the importance of fluid-electrolyte balance and acid-base balance.
10. Explain the mechanism and chemistry of excretion.
11. Explain the properties and function of blood, and the mechanism of acquired and passive immunity.
12. Describe the mechanics of respiration and transport of oxygen and carbon dioxide.
13. Describe the mechanism and chemistry of digestion.
14. Analyze the physiology of food absorption.
15. State the chemistry of foodstuffs including carbohydrate, lipids, proteins, vitamins and minerals.
16. Describe the mechanism of body temperature control.
17. Define a hormone and understand general function and action of hormones.
18. Relate vertebrate physiology with medicine and associated health sciences.
TEXTBOOK LECTURE TOPICS:
1. The study of body function Introduction to physiology, homeostasis and feedback control. Page 1-21.
2. Chemical composition of the body -Atoms, ions and chemical bonds. Carbohydrates, lipids and proteins. Page 22-44.
3. Cell structure and genetic control- Cell membrane, cytoplasm, nucleus, protein and DNA synthesis. Page 46-79.
4. Enzymes and energy- Enzymes as catalysts, control of enzyme activity, and bioenergetics. Page 82-99.
5. Cell respiration and metabolism. Glycolysis and lactic acid pathway, aerobic respiration and metabolism of lipids and proteins. Page 100-120.
6. Membrane transport and the membrane potential. Page 122-140.
7. The nervous system: organization, electrical activity and synaptic transmission. Page 142-176.
8. The central nervous system. Page 178-205.
9. The autonomic nervous system. Page 206-225.
10. Sensory physiology: characteristics of sensory receptors, cutaneous sensations, taste and olfaction, vestibular apparatus and equilibrium, the ear and hearing, the eyes and vision. Page 226-254.
11. Endocrine glands: secretion and action. Mechanism of hormone, pituitary gland, adrenal glands, thyroid and parathyroid glands, pancreas and other endocrine glands, autocrine and paracrine regulation. Page 270-304.
12. Muscle: mechanisms of contraction and neural control. Page 306-329.
13. Heart and circulation. Page 342-383.
14. Cardiac output, blood flow, and blood pressure. Page 386-422.
15. The immune system. Page 424-456.
16. Respiratory physiology. Page 458-502.
17. Physiology of the kidneys. Page 504-537.
18. The digestive system. Page 538-574.
19. Regulation of metabolism. Page 576-596.
20. Reproduction: sexual reproduction, endocrine regulation, male and female reproductive systems, menstrual cycle, fertilization, pregnancy and parturition.
INTERACTIVE WEB TUTORIAL:
http://www.nlm.gov/medlineplus/tutorial.html
EVALUATION:
Assessment/evaluation is necessary to see that all objectives as outlined above in General Objectives are met. The semester grade will be based on the average score of five tests including the mid-term and the final. There will be two special library assignments on the relevant topic of human physiology. However, there will be no extra credit given to any student during the course. The laboratory reports and examinations will constitute 25% of the overall grades. The lecture-discussion component of this course constitutes 75% of the final grade. Final grades will be determined as follows:
90% or above = A
80% to 89.9% = B
70% to 79.9% = C
60% to 69.9% = D
59.9% or below = F
1. Attendance Policy and Administrative Withdrawal: Good attendance is essential in order to accomplish the objective of the course. Students are required to attend class and lab regularly, punctually, and not to leave the class early without the permission of the instructor. Any student leaving early without prior permission will be marked absent. Dean will be informed of the attendance report on a weekly basis.
The attendance record in POISE will be used to enforce the college's attendance policy.
2. Examination Policy: Examination will be given only on the day they are scheduled. No make-up tests will be given to students unless prior arrangement is made with the instructor.
3. Assignments: Students are required to complete the assignments within the time frame set by the instructor. The instructor is under no obligation to accept the late assignments.
REFERENCE BOOKS AND JOURNALS:
BOOKS
Elaine Marieb N. Human Anatomy and Physiology, The Benjamin/Cummings Publishing Company, Inc., Redwood City, CA
Guyton Arthur C. Human Physiology, W.B. Saunders Company, Philadelphia , PA.
Rhoades Rodney and Pflanzer Richard. Human Physiology, Saunders College Publishing, Philadelphia, PA
Rischer Carl E and Easton Thomas A. Focus on Human Biology. Harper Collins Publishers, Inc., New York, NY
Tortora Gerard J. Principles of Human Anatomy, Harper Collins Publishers, Inc., New York, NY.
Tortora Gerard J. Introduction to Human Body: The Essentials of Anatomy and Physiology, Harper Collins Publishers, Inc., New York, NY.
Sherwood Lauralee. Human Physiology: From Cells to Systems. Wadsworth Publishing Company, Albany, NY.
JOURNALS
American Journal of Physiology
American Biology Teacher
American Journal of Epidemiology
American Journal of Public Health
American Zoologist
Biology of Reproduction
Endocrinology
Human Biology
Journal of Andrology
Journal of Cell Biology
Journal of Embryology and Experimental Morphology
Journal of Experimental Biology
Journal of Experimental Zoology
Journal of Mammology
Molecular Biology of the Cell
Science
Scientific American
MULTIMEDIA RESOURCE (CD-ROM)
Essentials of Physiology. Editor: Thomas M. Nosek
Interactive Physiology: A.D.A.M. Benjamin/Cummings
ONLINE LEARNING CENTER
Human Physiology. For free Online Learning Center check out the website at http://www.mhhe.com/biosci/ap/fox
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