Research & Grants

Research Interests

  • Reproductive toxicology
  • Cell adhesion molecules in the male gamete
  • Cell-cell and cell-matrix interactions in the male reproductive system

Current Research Activities

The Hypothesis: Reproductive toxicity in the male by polychlorinated aromatic hydrocarbons (PAHs) involves direct effects on testicular cells. In vitro effects of PAHs on Sertoli cells and spermatogenic (germ) cells are currently under investigation. The hypothesis is that PAHs cause decreased viability of both Sertoli cells and germ cells and alter Sertoli cell-germ cell adhesion mechanisms. Results from this investigation will provide insight into our understanding of the manner in which PAHs environmental pollutants act to interfere with spermatogenesis.

Research Grants


  • NIH/NIGMS (8/1/98-7/31/02)
  • MBRS SCORE Grant Number: 2 S06 GM08117-24A1 (8/1/98-7/31/99)
  • NIH/Academic Research Enhancement Award (9/15/99-9/14/02). "Male Reproductive Toxicity and Estrogenicity of PAHs.


Benedict College MBRS SCORE (Support of Continuous Research Excellence) Program consists of a research project that is directed by Dr. Raychoudhury. A collaborative research and learning environment has been developed within the program. The College MBRS Advisory Committee evaluates progress and assists in achieving goals of the Program. Over 95% of faculty members in the Department of Biological and Physical Sciences have terminal degree in their respective discipline. Most of them have received postdoctoral and other research training. The recent restructuring of research laboratories, the development of new research facilities, and the renewed support from the administration, have provided a great opportunity for faculty to expand MBRS SCORE research activities. The infrastructure for biomedical research at Benedict College has significantly been increased. Thus the scope for research collaboration with other major schools in the state has expanded manifold.


The biology faculty supported under the AREA program is benefited from the opportunity to conduct independent research at Benedict College. This program has strengthened research capability of the institution, and thereby furthered research participation of students. Our goal is to increase participation of undergraduate students in biomedical research. A good number of students are engaged in biomedical research to prepare them for graduate schools and professional programs. In-house research-rich environment help them to present their research from Benedict College to regional and national meetings. Students from middle and high schools also receive research training in our research laboratories.


Through the summer residency program undertaken by our biology faculty Benedict College has received the EARDA grant from the National Institute of Health. The objectives of the program are summarized as follows: (a) enhance faculty opportunities to conduct biomedical and behavioral research and research training; (b) develop skills in fundamentals of preparing research grant applications; (c) aid undergraduate institution in developing collaborative arrangements with other major schools; and (d) assist in effectively guiding students towards careers in science and research. The major focus addresses strategies for attracting underrepresented undergraduate minority students into research experiences that will lead to biomedical research careers.

For Additional Information:
Contact: Dr. S. Raychoudhury, Director, Research and Development
Phone: (803) 255-1781/ (803) 253-5279; Fax: (803) 253-5068
Or e-mail: sraychoudhury@crle.com

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